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Several supposed health effects of cocoa have been considered, including improved heart function and relief of angina pectoris , stimulation of the nervous system, facilitated digestion, and improved kidney and bowel function. In addition, cocoa has been used to treat anemia, mental fatigue, tuberculosis , fever, gout, Jimmy Choo Embossed CapToe Pumps Free Shipping Cheapest Price KMW2K
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In the 19th century, chocolate became a luxury item. Hence, its consumption was a sin rather than a remedy. Nowadays, chocolate is associated with obesity, high blood pressure and diabetes because most chocolate that’s consumed is loaded with sugars and other chemicals. Therefore, many physicians currently tend to warn patients about the potential health hazards of consuming large amounts of chocolate-based nutrients.

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Have you heard that you should not give dogs chocolate? Here’s why: Cacao beans contain theobromine , which makes up 1 percent to 2 percent of the cacao bean. It’s a nervous system stimulant that dilates the blood vessels similar to how Bettye Muller PeepToe Slingback Pumps Genuine Sale Online xlpnb5uqIY
affects the body. This is the ingredient that makes cacao and chocolate unsafe for dogs. If you’re sensitive to caffeine, causing you to have anxiety or affect your sleep, you may want to be careful about how much cacao you consume, if any.


Another important fact is that some think that cocoa provides calcium — however, oxalic acid is a compound found in cacao that inhibits the absorption of calcium. So though there is calcium in cacao, it’s not considered a good calcium source for this reason. In any case, you get more of the calcium by eating cacao than if you eat processed chocolate, because the sugar found in chocolate takes calcium reserves from the body.

Cacao also contains a high amount fat and calories. Consume in moderation, and be ultra-aware when combining with other calorie-dense foods so you don’t over do it. And if you have an allergic reaction, stop consuming it immediately and check with your doctor.

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Dopamine innervation in the thalamus: Monkey versus rat

et al.
Cerebral Cortex (2009) 19(2) 424-434



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We recently identified the thalamic dopaminergic system in the human and macaque monkey brains, and, based on earlier reports on the paucity of dopamine in the rat thalamus, hypothesized that this dopaminergic system was particularly developed in primates. Here we test this hypothesis using immunohistochemistry against the dopamine transporter (DAT) in adult macaque and rat brains. The extent and density of DAT-immunoreactive (-ir) axons were remarkably greater in the macaque dorsal thalamus, where the mediodorsal association nucleus and the ventral motor nuclei held the densest immunolabeling. In contrast, sparse DAT immunolabeling was present in the rat dorsal thalamus; it was mainly located in the mediodorsal, paraventricular, ventral medial, and ventral lateral nuclei. The reticular nucleus, zona incerta, and lateral habenular nucleus held numerous DAT-ir axons in both species. Ultrastructural analysis in the macaque mediodorsal nucleus revealed that thalamic interneurons are a main postsynaptic target of DAT-ir axons; this suggests that the marked expansion of the dopamine innervation in the primate in comparison to the rodent thalamus may be related to the presence of a sizable interneuron population in primates. We remark that it is important to be aware of brain species differences when using animal models of human brain disease.

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Miguel Ángel García-Cabezas

Patricia Martínez-Sánchez

Miguel Ángel Sánchez-González

Miguel Garzón

Carmen Cavada

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García-Cabezas, M. Á., Martínez-Sánchez, P., Sánchez-González, M. Á., Garzón, M., Cavada, C. (2009). Dopamine innervation in the thalamus: Monkey versus rat. Cerebral Cortex , 19 (2), 424–434. https://doi.org/10.1093/cercor/bhn093

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